
Trifluoperazine dihydrochloride
CAS No. 440-17-5
Trifluoperazine dihydrochloride( TFP | SKF5019 )
Catalog No. M14498 CAS No. 440-17-5
An antiadrenergic, antidopaminergic and anticholinergic agent.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
100MG | 45 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameTrifluoperazine dihydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionAn antiadrenergic, antidopaminergic and anticholinergic agent.
-
DescriptionAn antiadrenergic, antidopaminergic and anticholinergic agent; is identified as an inhibitor that disrupts the S100A4/myosin-IIA interaction; block S100A4-mediated disassembly of myosin-IIA filaments, and promote S100A4 oligomerization.Schizophrenia Approved(In Vitro):Trifluoperazine dihydrochloride is a long-established, widely used 'conventional' antipsychotic agent. Trifluoperazine dihydrochloride has been an extensively studied drug molecule that has been used as a calmodulin inhibitor.Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis, but not budding, by disturbing cellular CaM and/or CaM-dependent functions.
-
In VitroTrifluoperazine dihydrochloride is a long-established, widely used 'conventional' antipsychotic agent. Trifluoperazine dihydrochloride has been an extensively studied drug molecule that has been used as a calmodulin inhibitor.Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis, but not budding, by disturbing cellular CaM and/or CaM-dependent functions.
-
In Vivo——
-
SynonymsTFP | SKF5019
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
RecptorD2
-
Research AreaNeurological Disease
-
IndicationSchizophrenia
Chemical Information
-
CAS Number440-17-5
-
Formula Weight480.4174
-
Molecular FormulaC21H26Cl2F3N3S
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESFC(C(C=C1N2CCCN3CCN(C)CC3)=CC=C1SC4=C2C=CC=C4)(F)F.[H]Cl.[H]Cl
-
Chemical Name10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-, hydrochloride (1:2)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Malashkevich VN, et al. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8605-10.
2. Huerta-Bahena J, et al. Mol Pharmacol. 1983 Jan;23(1):67-70.
3. Creese I, et al. J Neuropsychiatry Clin Neurosci. 1996 Spring;8(2):223-6.
molnova catalog



related products
-
Ropinirole hydrochlo...
Ropinirole a selective dopamine D2 receptors agonist with Ki of 29 nM.
-
ABT-724
ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM).
-
Clozapine
An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.